Cellular Toxicity

Cellular toxicity is a major problem and can result in organ dysfunction and cause many severe health problems. Various studies have shown that toxicants, toxic substances in the environment, may stimulate the over production of nitric oxide, reactive oxygen species, and the subsequent oxidative stress which leads to death in cells. The cytotoxicity of drugs leads to mitochondrial dysfunction and, subsequently, oxidative stress which has been recognized as a contributing factor in further cell death. Pharmaceuticals can sometimes cause damaged DNA which will also lead to cellular toxicity.

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